Compound
1 ml of Tantum rose solution contains benzydamine (in hydrochloride form) 1 mg. Additive components: ethyl alcohol, trimethyl acetylammonium para-toluenesulfonate, rose oil, prepared water.9.44 g of Tantum rose granules contain benzydamine (in hydrochloride form) 0.5 g. Additive components: povidone, trimethylacetylammonium para-toluenesulfonate, sodium chloride.
pharmachologic effect
The active substance is an indazole derivative, it belongs to anti-inflammatory drugs with a non-steroidal structure. Benzydamine has a membrane stabilizing effect, enhances the recovery processes in the epithelial cells of the vagina.By improving the condition of the vaginal mucosa, it enhances the natural protective functions against pathogens. Thanks to this action, there is a significant effectiveness of the drug in erosive lesions in gynecology. The substance inhibits the synthesis of prostaglandin molecules, provokes the inhibition of COX with a weakening of the development of the inflammatory reaction.
Tantum rose has a strong anti-inflammatory effect, has an analgesic effect, eliminates tissue edema by eliminating the pathological permeability of the vascular endothelium. The drug acts as an antiseptic, including against gardnerella.
The active component has a strong penetrating ability, which provides high bioavailability to the foci of inflammation with a quick implementation of the therapeutic effect. It is optimal to combine the drug Tantum Rose with other therapeutic agents to increase the effectiveness of treatment regimens and reduce the duration of therapy courses. Benzydamine is excreted in the metabolized form through the intestines and kidneys.
Indications for use
Tantum rose is prescribed for:- vaginosis associated with bacterial infection;
- vulvovaginitis of a specific nature (in treatment regimens);
- vulvovaginitis of a nonspecific nature;
- inflammatory diseases in gynecology associated with the passage of radiotherapy, chemotherapy treatment;
- cervicovaginitis of various etiology;
- prevention of the development of inflammation and infection in surgical gynecology (used before and after surgery);
- hygiene in the period after childbirth.
Mode of application
Tantum rose is indicated for intravaginal use. When using powder, it is necessary to dilute the contents of 1 sachet in 0.5 l pure water... The resulting solution is used in the same way as Tantum rose in the form of a solution. For one douching, you need to use about 140 ml of the finished dosage form.When using a solution from a bottle, it is shown to use all its contents at one time for douching. The bottle is kept in a water bath to warm up to body temperature. The introduction of the medicinal fluid is carried out in the supine position. Retention must be ensured medicinal solution into the vagina for a few minutes. Treatment regimens for various indications:
Side effects
In the official documentation, the occurrence of adverse reactions during therapy with Tantum rose was not reported. It is theoretically possible to develop hypersensitivity reactions.Contraindications
Tantum rose is not prescribed for:- indications in pediatrics (up to 12 years old);
- hypersensitivity to the active ingredient;
- hypersensitivity to additive components of the dosage form.
Pregnancy
Tantum rose can be prescribed to pregnant women due to the absence of contraindications for the use of benzydamine in this group of patients. Only the attending specialist can prescribe the drug and give recommendations on the adequate use of this drug.Drug interactions
No negative interactions were noted. The drug is shown to be included in treatment regimens for inflammatory and infectious processes in gynecological practice to enhance the action of other chemotherapeutic agents.It is not recommended to use the solution simultaneously with other agents for intravaginal use to exclude the possibility of undesirable physicochemical interactions. Because of this, the use of intravaginal drugs is best divided over time.
Overdose
Cases of exceeding therapeutic dosages with the development of undesirable symptoms were not recorded. It is theoretically possible to increase the risk of developing hypersensitivity reactions to the active ingredient, especially with chronic overdose.Release form
Tantum rose comes in the form of a solution and powder for dilution and subsequent use. The packaging of the drug is as follows:- 140 ml solution × 5 bottles with special nozzles and cannulas / cardboard packaging;
- 9.44 g of powder × 10 sachets / cardboard packaging.
Storage conditions
The storage temperature of the sachet and solution is up to 25 degrees Celsius. The suitability of both forms of release for use is 5 years. The diluted powder must be stored for as short a time as possible.Synonyms
Tantumverde, Tenflex.Nosological classification (ICD-10)
Inflammatory disease of the cervix (N72)
Result: positive feedback
Good remedy.
Benefits: It helps well, very effective, restores microflora.
Disadvantages: Complicated preparation for the procedure, expensive means.
For a long time I could not cure a cold, the doctor prescribed strong antibiotics for me. I had never been treated like this before, and I did not know what to expect from them. As a result, it was necessary to restore the microflora of the intimate zone. It so happened that after taking antibiotics, there was discomfort in the intimate area, first discharge, a strange smell, then itching (or burning). Very unpleasant sensation and terribly embarrassing to go to the gynecologist. The gynecologist diagnosed with vaginitis. Prescribed candles and Tantum Rose solution. This medicine is available as a finished medicine and in powder. The solution of Tantum Rose had to be treated within 10 days. 5 bottles are sold in one package. The doctor prescribed the treatment regimen - once a day and preferably in the evening after a bath. As soon as I took out the bottle from the package, it immediately smelled of a rose, a very pleasant aroma. It is quite difficult to open the bottle, I did not immediately understand how to open it, although the doctor explained it. The solution should be warm, but not hot; you can warm it up in a water bath. You need to use (spray) it carefully, there is a chance to completely spill it. After 10 days of use, everything went away and after the first time, there was a feeling of complete cleanliness.
Result: positive feedback
Effective for thrush
Advantages:
Flaws:
Tantum rose was prescribed to me by a gynecologist, who is an adjunct in the treatment of thrush. It is sold in two forms, powder and ready-to-use solution. I purchased it in the form of a powder, and it was difficult for me to figure out how to dilute it correctly and how to carry out the procedure correctly. Through trial and error, I learned, and the remedy turned out to be effective. After douching, an unpleasant burning sensation is felt for several minutes, but then everything goes away quickly. In a few steps, the symptoms of thrush, such as itching and burning, disappeared. A big plus for this drug is that it has no contraindications (except childhood up to 12 years old) and side effects.
Result: positive feedback
Benefits: has antiseptic, anti-inflammatory properties.
Disadvantages: Not found
After treating my cold with antibiotics, I started having candidiasis (thrush). My sister recommended Tantum rose liquid to me and told me how to use it. She already had experience in treating vaginitis with this drug. The course required 2 packs, 10 vials. The powder is much cheaper, but the bottles are more convenient to use. And they are made in the form of a pear with a tip, just for internal irrigation. The medicine comes with detailed instructions and it's easy to figure it out. When you open the bottle, you immediately feel the aroma of a blooming rose hip. From the first procedure I felt relief, the burning sensation disappeared. Tantum rose is a medicine for women. It can also be used for hygienic purposes.
Result: negative feedback
From inflammatory processes
Benefits: Ease of use, efficiency
Disadvantages: Price bites a little
In the summer I rested at the sea, swam, sunbathed on the beach, and a week later the result appeared: there were signs of inflammation and discomfort. A gynecologist friend advised me to take an anti-inflammatory - Tantum rose, in the pharmacy it turned out that it was sold in two forms - a solution with a pear for douching and a powder in a sachet for preparing the solution on your own. I took the first option - 5 pears with an antiseptic liquid in a package for about 700 rubles. Although the powder is two times more economical than the ready-made solution. I took Tanutm rose precisely because the active substance is not an antibiotic. I didn't immediately figure out how to open it - you need to remove the cap and pull the nozzle up. The aroma, by the way, is delicious - it smells like rose oils. The inflammation and itching disappeared, I used it at night. A month later I gave up for a check - everything is fine.
Result: positive feedback
Accelerates recovery and makes you feel better
Benefits: Immediately relieves symptoms of the disease, accelerates recovery, does not cause discomfort, smells good
Disadvantages: Expensive, seldom sold
I had never heard of this remedy before, but a paid gynecologist prescribed it for the treatment of vaginosis. I barely found it, to be honest, and this powder was not very cheap. There are 10 bags of powder inside the package, and the solution is very easy to prepare. You dissolve the powder in boiled water (it dissolves quickly), and then you have to do douching. The solution itself is colorless, but it smells very nice of something sweet. It does not cause any unpleasant sensations like a burning sensation, on the contrary - after the first treatment, the itching, and the burning sensation, and the pain subsided greatly, which greatly eased both my condition and life in general. Of course, I was also treated with antiseptics in the form of tablets, the solution is not used alone, but I understood its effectiveness immediately. I had vaginosis before, and some pills eliminated it in 8-10 days. Now, with the help of Tantum roses, I managed to recover in just 5 days. This is not surprising, because the agent hits "right on target", where the microbes live, and destroys them directly while the tablets are absorbed and digested. The drug has no side effects at all, so I advise you to try it, if it's not a pity for the money.
Among the huge assortment of medicines and drugs, special emphasis is placed on drug groups intended for use in the field of gynecology, including surgery. One of these is Tantum Rose, a non-steroidal drug with a pronounced anti-inflammatory effect and recommended for topical use (douching). For informational purposes, we offer you in this article about the composition of the powder, what pharmacokinetics and indications / contraindications for the medicine Tantum Rose, as well as what instructions for its use contain.
The anti-inflammatory and antibacterial drug Tantum Rose is actively used in gynecology to solve health problems related to the reproductive system. Douching, for which a solution based on this powder is used, helps to eliminate inflammatory processes, infections (fungal, Trichomonas) affecting the vagina.
Pharmacological components of the powder
Acting as an effective anti-inflammatory medical gynecological drug intended for the preparation of vaginal solution, homogeneous powder Tantum Rose belongs to the group of indosols. The main component of the drug is benzydamine, or rather, benzydamine hydrochloride. 500 mg of this substance is contained in each sachet. The powder is a homogeneous white granule without any extraneous elements or shades.
The auxiliary components are:
- NaCl;
- polyvinylpyrrolidone.
Tantum Rose powder is sold in the form of cardboard boxes containing 10 sachets. Also, each package contains instructions for use, preparation of the solution. Tantum Rose is also available as a ready-to-use formulation (0.1% solution). The main component of the finished substance remains the same (benzydamine hydrochloride), but the auxiliary chemical elements of the solution include:
- trimethyl acetylammonium p-toluenesulfonate;
- ethyl alcohol (96% ethanol);
- polysorbate;
- water prepared by a special method;
- 0.005 ml of rose oil.
How does the drug work?
Pharmacodynamics of the drug does not affect the body as a whole, since Tantum Rose is a non-steroidal substance that acts in a specific place. In this case, taking into account the gynecological field of application, the solution of Tantum Rose powder must be applied invaginally (douching).
The mechanism of action of the composition is that Tantum Rose (powder for the preparation of invaginal composition) causes stabilization of cell membranes, simultaneously suppressing the synthesis of substances from the group of physiological lipids. Due to its main active substance (benzydamine), the solution begins to act very quickly, penetrating the membranes of microorganisms, damaging their structure and disrupting the internal metabolism of cells, contributing to their decay. At the same time, the finished composition increases the resistance of epithelial tissue to pathogens. Also, due to the histoprotective activity of the drug Tantum Rose, healing and scarring of erosive lesions inside the vagina occurs faster, which significantly improves the natural healing process of scars, ulcers and other wounds that appeared during surgery.
As for the drug in a diluted form, its pharmacokinetics have a local beneficial effect. During douching, a solution based on Tantum Rose powder easily enters the tissues and membranes inside the uterus, being absorbed in the ecclesiastical or vulvo-vaginal areas. As part of blood plasma medicinal product can be detected about half an hour after douching, and the solution is excreted from it within 7.5 hours with urine. The systemic action of Tantum Rose is not characterized, which makes it possible to use it even during lactation, during pregnancy.
Benzydamine, as the active substance of Tantum Rose, generally has an effect:
- anti-inflammatory;
- antibacterial;
- analgesic;
- antiexudative;
- antifungal (for the Candida albicans group);
- prevents the reproduction of pathogens.
The drug Tantum Rose, 1% concentration ready-to-use solution for invaginal douching has several cases for recommendation. The instruction attached to this tool states that the indications for its use are as follows:
- Pathological inflammatory processes that destroy the microflora of the vagina ();
- Vulvovaginitis (specific and nonspecific);
- Cervicovaginitis;
- As a prophylactic agent for complications accompanying the preoperative or postoperative period.
At the same time, the drug has contraindications. Solution based on Tantum Rose powder is not recommended:
- children under 12 years old;
- patients who have increased individual sensitivity to the drug or its individual components.
How is the medicinal solution used?
Dosage and recommendations for the use of the drug Tantum Rose depends on the nature of the disease. In order to use the powder for its intended purpose (intravaginally), a solution should be prepared. For this, the contents of the sachet are poured into 0.5 liters. warm water(pre-boiled). Irrigation should be carried out only in the supine position, so that the composition remains inside the vagina for some time.
Depending on the patient's diagnosis, douching with the ready-made composition of Tantum Rose should be:
- 1-2 p within 24 hours for 7-10 days at inflammatory disease(bacterial vaginosis);
- 2 r for 24 hours for 10 days with vulvovaginitis (nonspecific, specific) and cervicovaginitis;
- 1 r for 24 hours for 3-5 days as a prophylactic agent.
additional information
The instructions for the Tantum Rose invaginal irrigation medication have additional information. In particular, it contains a warning that it is not recommended to use the Tantum douche for a long time, so as not to cause increased sensitivity inside the vagina.
With regard to side effects, sometimes patients may experience drowsiness. In some cases, allergic reactions occur. However, there have been no reports of serious side effects and overdose to date. There were no negative reviews regarding the use of Tantum Rose solution for invaginal irrigation during lactation or during pregnancy.
Thrush is treated with local and systemic drugs. The decision on the advisability of using a particular tool is made by a qualified specialist. This largely depends on the form of the pathological process, the severity of the course, the age of the patient. Tantum rose with thrush is local drug, which doctors use in complex therapy.
In general, this medicine is widely used in gynecological practice, and this is explained by the provision of such an effect on the body:
- anti-inflammatory;
- analgesic;
- antiseptic.
Local drugs can be prescribed in combination with systemic agents, or may be indicated for separate use. Usually, the second option is justified for newly diagnosed thrush, which is mild.
Candidal lesion has a tendency to relapse, so treatment should be comprehensive, competent and timely. It is extremely important to heal to the end, even if they disappeared, this does not mean that the disease has completely receded. The treatment should be carried out by a specialist on the basis of laboratory data. Self-medication can threaten the transition to and the occurrence of complications, for example, infertility.
Tantum Rose is medicine, which should be used after being prescribed by a doctor. Be sure to read the instructions and follow their instructions.
Tantum rose: instructions for use
The main component of the drug is benzydamine hydrochloride. The product is produced in two dosage forms:
- intravaginal solution. Has a pleasant rose scent;
- powder for solution preparation in the form of white homogeneous granules.
Indications and contraindications
Tantum Rose is appointed by specialists in the following cases:
- vulvovaginitis;
- cervicovaginitis;
- for hygiene procedures;
- after surgery in case of complications.
Any medication has a number of its limitations, tantum rose is no exception:
- children under twelve years old;
- hypersensitivity to the constituents of the product.
How to use Tantum Rose?
The drug is used intravaginally. If you purchased a powder, then one package is diluted in half a liter of water.
To carry out douching, you will need one hundred and forty grams of the medicinal solution. Beforehand, the liquid should be slightly warmed up. It is best to carry out the procedure while lying down, it is important that the solution is in the vagina for several minutes.
An important feature of the drug is the absence of side effects, but this is subject to the treatment regimen. Long-term use is not recommended, as a hypersensitivity reaction may develop. If after the expiration of the treatment period indicated by the doctor, there are no results, it is necessary to consult with the doctor to adjust the treatment.
Analogs Tantum rose
Before using tantum rose substitutes, it is important to discuss the appropriateness of this solution with your doctor. Consider six analogues of this drug:
- Bronflex. Available as a dosed topical spray. Has a wide range of its effects on the body: anti-inflammatory, antibacterial, antiseptic, antifungal, local anesthetic;
- Oralsept. Refers to the group of non-steroidal anti-inflammatory drugs;
- Tantum Verde. Available in the form of tablets for resorption, solution and spray;
- Tenflex. Available in two dosage forms: spray and solution.
So, tantum rose for thrush is a drug with a wide spectrum of action, which is used in the treatment of candidiasis. The medicinal substance acts on the causative agents of the disease, leading to their death. The tool quickly eliminates unpleasant clinical symptoms, relieving the condition of patients. Do not use tantum rose as self-medication, undergo a comprehensive examination and follow all the doctor's prescriptions!
Tantum Rose: instructions for use and reviews
Tantum Rose is a local preparation with anti-inflammatory, analgesic, antiseptic action, used in gynecological practice.
Release form and composition
Dosage forms of release:
- vaginal solution: has a characteristic smell of roses, transparent, colorless (in polyethylene bottles of 140 ml, 5 bottles in a cardboard box, complete with a guide nozzle and a cannula);
- powder for the preparation of vaginal solution: white homogeneous granules, foreign particles and lumps are absent (9.44 g each in a sachet of polypropylene and paper, 10 sachets in a cardboard box).
Each pack also contains instructions for the use of Tantum Rose.
Composition of 1 ml of vaginal solution:
- active substance: benzydamine hydrochloride - 1 mg;
- additional components: rose oil, polysorbate 20, trimethylacetylammonium-para-toluenesulfonate, 96% ethanol, purified water.
Composition of 1 powder sachet:
- active substance: benzydamine hydrochloride - 500 mg;
- additional components: povidone, trimethylacetylammonium-para-toluenesulfonate, sodium chloride.
Pharmacological properties
Pharmacodynamics
Tantum Rose is a local non-steroidal anti-inflammatory drug, belongs to the indazole group. It has a local anesthetic and anti-inflammatory effect, has antiseptic, antibacterial and antifungal properties.
The mechanism of action of benzydamine is based on stabilization of cell membranes and inhibition of prostaglandin synthesis.
The substance has an antibacterial effect due to the rapid penetration of microorganisms through the membranes, further damage to cellular structures, disruption of metabolic processes and cell lysis.
It has an antifungal effect against Candida albicans. It leads to structural modifications of the cell wall of fungi and metabolic chains of mycetes, which prevents their reproduction.
Pharmacokinetics
When applied topically, benzydamine is well absorbed through the mucous membranes and penetrates into inflamed tissues.
Excretion is carried out mainly by the kidneys and through the intestines in the form of conjugation products or metabolites.
Indications for use
- specific vulvovaginitis (along with other drugs);
- bacterial vaginosis;
- nonspecific cervicovaginitis and vulvovaginitis of any genesis, including those secondary to radio- and chemotherapy;
- the postpartum period (as a hygiene product);
- complications in operative gynecology (prevention in the pre- and postoperative periods).
Contraindications
- age up to 12 years;
- hypersensitivity to the components of the drug.
Tantum Rose, instructions for use: method and dosage
The drug is used intravaginally.
Method for preparing a solution from Tantum Rose powder: the contents of 1 sachet should be dissolved in 500 ml water.
For douching, a solution of 140 ml is used, previously slightly warmed up in a water bath. The procedure should be performed while lying down, the solution should remain in the vagina for several minutes.
- bacterial vaginosis (vaginal irrigation): 1-2 times a day for 7-10 days;
- nonspecific vulvovaginitis and cervicovaginitis of any genesis, specific vulvovaginitis (along with other drugs): 2 times a day for 10 days;
- the postpartum period (as a hygienic means) and complications in operative gynecology (prophylaxis in the pre- and postoperative periods): once a day for a course of 3-5 days.
Side effects
The development of adverse reactions when using Tantum Rose according to the prescribed treatment regimen is usually not observed.
Overdose
There is no information.
special instructions
Without therapeutic effect after using the drug for the recommended period, you should consult a specialist.
Influence on the ability to drive vehicles and complex mechanisms
The use of Tantum Rose solution does not affect the ability to drive vehicles and does not interfere with activities that require a high concentration of attention and speed of psychomotor reactions.
Application during pregnancy and lactation
Tantum Rose solution (including those made from powder) is approved for use during pregnancy and during breastfeeding.
Childhood use
It is not recommended to use the drug for patients under 12 years of age.
Drug interactions
No clinically significant interaction of Tantum Rose solution and powder with other drugs / substances has been identified.
Analogs
Analogs of Tantum Rose are: Amintax, Polygynax, Betadin, Hexicon, Bifidumbacterin, Fitostimulin.
Terms and conditions of storage
Store in a dark place at temperatures up to 25 ° C. Keep out of the reach of children.
The shelf life is 5 years.